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The regeneration of bone defects caused by periodontal disease or trauma is an important goal. Porous hydroxyapatite (HA) is an osteoconductive graft material. However, the hydrophobic properties of HA can be a disadvantage in the initial healing process. HA can be coated with TiO2 to improve its hydrophilicity, and ultraviolet irradiation (UV) can further increase the hydrophilicity by photofunctionalization. This study was designed to evaluate the effect of 5% TiO2-coated HA on rabbit calvarial defects and compare it with that of photofunctionalization on new bone in the early stage. The following four study groups were established, negative control, HA, TiO2-coated HA, and TiO2-coated HA with UV. The animals were sacrificed and the defects were assessed by radiography as well as histologic and histomorphometric analyses. At 2 and 8 weeks postoperatively, the TiO2-coated HA with UV group and TiO2-coated HA group showed significantly higher percentages of new bone than the control group (p < 0.05). UV irradiation increased the extent of new bone formation, and there was a significant difference between the TiO2-coated HA group and TiO2-coated HA with UV group. The combination of TiO2/HA and UV irradiation in bone regeneration appears to induce a favorable response.

A high-quality organolead trihalide perovskite film with large-sized crystalline grains and smooth surfaces is required to obtain efficient perovskite solar cells (PSCs). Herein, high-quality (FAPbI3)0.97(MAPbBr3)0.03 perovskite films were fabricated using trimesic acid (TMA) additives in a halide perovskite precursor solution to obtain efficient PSCs. The X-ray diffraction analysis and scanning electron microscopy of the films revealed that the TMA had a significant effect on the roughness of the films by acting as a surface link, thus reducing the surface defects and recombination at the grain boundaries. In addition, with the addition of the TMA additive, a smooth perovskite film with a flat surface and no pinholes was obtained. The perovskite film was used to fabricate a PSC device, and the device exhibited a high power conversion efficiency of 17.26%, which was higher than that of the control device (15.15%) under the same conditions. This study demonstrates a facile method to passivate defects on the perovskite layer via surface modification.

The electron transport layer (ETL) of organic–inorganic perovskite solar cells plays an important role in their power conversion efficiency (PCE). In this study, TiO2 hollow nanospheres with a diameter of 150 nm were prepared by a facile synthesis method. The synthesized TiO2 hollow nanospheres had a highly porous structure with a surface area of 85.23 m2 g−1, which is significantly higher than commercial TiO2 (P25) (54.32 m2 g−1), indicating that they can form an ideal mesoporous layer for Formamidinium iodide-based perovskite solar cells (PSCs). In addition, the nanospheres achieved a remarkable perovskite performance, and the average PCE increased from 12.87% to 14.27% with a short circuit current density of 22.36 mAcm−2, an open voltage of 0.95 V, and a fill factor of 0.65. The scanning electron microscopy images revealed that the enhanced PCE could be due to the improved carrier collection and transport properties of the nanosphere, which enabled efficient filtration of perovskite into the TiO2 mesoporous ETL. The TiO2 hollow nanospheres fabricated in this study show high potential as a high-quality ETL material for efficient (FAPbI3)0.97(MAPbBr3)0.03-based PSCs.

The hydrophilicity of bone graft material generally used as a carrier can play an important role in regulating bone morphogenetic protein (BMP) expression at the bone graft site. The hydrophilicity, altering physicochemical properties, and enhancing biological capabilities, can be increased via surface modification through ultraviolet (UV) photofunctionalization and the effect on de novo osteogenesis could be further improved. Therefore, this study aimed to assess the effects of UV-irradiated TiO 2 -coated hydroxyapatite (HA) in combination with rhBMP-2 on bone regeneration in rabbit calvarial defects. The hydrophilicity of HA and TiO 2 -coated HA pellets was evaluated by measuring the contact angle of water droplets with UV irradiation. To compare de novo osteogenesis in rabbit calvarial defects, the rabbits were segregated into four different groups: negative control, HA, TiO 2 -coated HA, and TiO 2 -coated HA with UV; histomorphometric analysis and micro-computed tomography (μCT) imaging were performed after 4 and 8 weeks.In vivo analysis revealed that de novo osteogenesis occurred on the critical size defects in all groups and was significantly increased in the TiO 2 -coated HA with UV group than in other groups (p < 0.05). The present results indicate that UV photofunctionalization promotes de novo osteogenesis.