The short EUROHIS-QOL 8-item index showed good cross-cultural field study performance and a satisfactory convergent and discriminant validity, and can therefore be recommended for use in public health research. In future studies the measure should also be tested in multinational clinical studies, particularly in order to test its sensitivity.

Zusammenfassung. Der Beitrag berichtet über die teststatistische Prüfung und Normierung der deutschen Versionen des EUROHIS-QOL 8 Item Index (EUROHIS-QOL) zur Erfassung der generischen Lebensqualität und des Wohlbefindens-Index der WHO (WHO-5) zur Erfassung der Wohlbefindens aus Sicht der Befragten. Datengrundlage bildet eine repräsentative Stichprobe der bundesdeutschen Bevölkerung aus dem Jahr 2004. Die teststatistische Prüfung verweist auf gute psychometrische Eigenschaften des EUROHIS-QOL Index. Obgleich Modifikationsmöglichkeiten bestehen, wird die Selektion von Items ausgeschlossen, weil dies den komzeptuellen Vorgaben der Indexkonstruktion widersprechen würde. Die Ergebnisse der teststatistischen Prüfung des WHO-5 sind hinsichtlich der psychometrischen Eigenschaften als ausgezeichnet einzuschätzen. Erstmals werden geschlechts- und altersgruppenspezifische Normwerte für die deutschsprachigen Versionen der beiden Instrumente vorgelegt.

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As quality of life (QoL) research is increasingly focusing on children and adolescents with haemophilia, the need for both age-appropriate and disease-specific assessment tools becomes apparent. Therefore, a set of questionnaires measuring QoL in children and adolescents with haemophilia was simultaneously developed in six languages within the European Haemo-QoL project (Haemophilia, 8, 2002, 47; Haemophilia, 10, 2004, 17). For implementation in larger studies and for use in daily clinical routine, a both short and psychometrically robust version of the questionnaire is needed. Using from the Haemo-QoL field study complete data sets of 306 children and adolescents (4-16 years) and their parents, a multivariate approach of item selection was applied to construct an eight-item instrument, the Haemo-QoL Index. The instrument is applicable to different age groups and represents the core content as well as the multidimensional structure of the original long versions. According to preliminary analyses, the index's psychometric performance concerning reliability and convergent validity is good. Further validation of the instrument's performance on a new and independent sample is needed.

Psychosocial, emotional, and physical problems can emerge after traumatic brain injury (TBI), potentially impacting health-related quality of life (HRQoL). Until now, however, neither the discriminatory power of disease-specific (QOLIBRI) and generic (SF-36) HRQoL nor their correlates have been compared in detail. These aspects as well as some psychometric item characteristics were studied in a sample of 795 TBI survivors. The Shannon H ' index absolute informativity, as an indicator of an instrument's power to differentiate between individuals within a specific group or health state, was investigated. Psychometric performance of the two instruments was predominantly good, generally higher, and more homogenous for the QOLIBRI than for the SF-36 subscales. Notably, the SF-36 “Role Physical,” “Role Emotional,” and “Social Functioning” subscales showed less satisfactory discriminatory power than all other dimensions or the sum scores of both instruments. The absolute informativity of disease-specific as well as generic HRQoL instruments concerning the different groups defined by different correlates differed significantly. When the focus is on how a certain subscale or sum score differentiates between individuals in one specific dimension/health state, the QOLIBRI can be recommended as the preferable instrument.