A biosensor can be defined as a compact analytical device or unit incorporating a biological or biologically derived sensitive recognition element immobilized on a physicochemical transducer to measure one or more analytes. Microfluidic systems, on the other hand, provide throughput processing, enhance transport for controlling the flow conditions, increase the mixing rate of different reagents, reduce sample and reagents volume (down to nanoliter), increase sensitivity of detection, and utilize the same platform for both sample preparation and detection. In view of these advantages, the integration of microfluidic and biosensor technologies provides the ability to merge chemical and biological components into a single platform and offers new opportunities for future biosensing applications including portability, disposability, real-time detection, unprecedented accuracies, and simultaneous analysis of different analytes in a single device. This review aims at representing advances and achievements in the field of microfluidic-based biosensing. The review also presents examples extracted from the literature to demonstrate the advantages of merging microfluidic and biosensing technologies and illustrate the versatility that such integration promises in the future biosensing for emerging areas of biological engineering, biomedical studies, point-of-care diagnostics, environmental monitoring, and precision agriculture.

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Autonomous vehicles (AV) are expected to improve, reshape, and revolutionize the future of ground transportation. It is anticipated that ordinary vehicles will one day be replaced with smart vehicles that are able to make decisions and perform driving tasks on their own. In order to achieve this objective, self-driving vehicles are equipped with sensors that are used to sense and perceive both their surroundings and the faraway environment, using further advances in communication technologies, such as 5G. In the meantime, local perception, as with human beings, will continue to be an effective means for controlling the vehicle at short range. In the other hand, extended perception allows for anticipation of distant events and produces smarter behavior to guide the vehicle to its destination while respecting a set of criteria (safety, energy management, traffic optimization, comfort). In spite of the remarkable advancements of sensor technologies in terms of their effectiveness and applicability for AV systems in recent years, sensors can still fail because of noise, ambient conditions, or manufacturing defects, among other factors; hence, it is not advisable to rely on a single sensor for any of the autonomous driving tasks. The practical solution is to incorporate multiple competitive and complementary sensors that work synergistically to overcome their individual shortcomings. This article provides a comprehensive review of the state-of-the-art methods utilized to improve the performance of AV systems in short-range or local vehicle environments. Specifically, it focuses on recent studies that use deep learning sensor fusion algorithms for perception, localization, and mapping. The article concludes by highlighting some of the current trends and possible future research directions.

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