PURPOSE: Old adults with mild cognitive impairment (MCI) are at high risk for developing dementia. Exercise is a promising intervention for cognitive decline. This study evaluated the effects of exercise interventions on cognitive adaptation for older adults with MCI and attempted to identify which specific modality of exercise is more effective.METHODS: National Assembly library, Research information sharing service, Google scholar databases from 1 January 2010 to 31 Oct 2020 were utilized for searching articles related to research purpose. Meta-analysis was conducted with Comprehensive Meta-Analysis 2.0 using the fixed-effect model for the available data without significant heterogeneity, or the random-effect model was used if appropriate.RESULTS:Through meta-analysis in 13 studies, the combination of aerobic and resistance movements significantly improved cognitive ability and showed that intervention in a particular week and time is of paramount importance to improving cognitive function.CONCLUSIONS: The Combination of aerobic and resistance exercise led to an improvement in cognitive ability and had a positive effect with a middle effect size on cognitive function in older adults with MCI.
PURPOSE: Cancer-related cognitive impairment (CRCI) is exposed to cognitive impairments that interfere with their daily lives after a complete recovery. Exercise is one of the effective non-pharmacological treatments to prevent or improve cognitive function decline. This study evaluated the effects of exercise interventions on cognitive function improvement in CRCI breast cancer patients and searched the association of various aspects in which exercise affects cognitive function improvement.METHODS: PubMed, ScienceDirect, ACS journal, and Google scholar databases from 1 January 2014 to 31 May 2021 were utilized for searching articles related to research purpose. Meta-analysis was conducted with Comprehensive Meta-Analysis 2.0 using the random-effect model.RESULTS: A meta-analysis of seven studies showed that walking (ES=0.59, p=.000) was the most effective in improving cognitive function, and moderate-intensity (ES=0.60, p=.000) was more effective than moderate-to-high intensity (ES=0.27, p=.007) exercise in CRCI patients with breast cancer. Cognitive function improvement was observed in short-term exercise intervention for four weeks (ES=0.46, p=.038), and after that, it was found that the cognition improvement effect was maintained or improved through long-term (12 or 24 weeks) exercise. Moreover, the cognitive function of CRCI patients with breast cancer improved without supervision during exercise interventions (ES=0.39, p=.001).CONCLUSIONS: Walking and moderate-intensity exercise can suppress cognitive impairment in CRCI patients with breast cancer. Personalized exercise prescription through short-term and long-term exercise periods can alleviate cognitive decline and improve the cognitive function of CRCI breast cancer patients. Exercise interventions without supervision also show a positive influence on cognitive function improvement.
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