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More than ninety phenylphenol derivatives were tested for fungistatic activity toward ten species of agriculturally important fungi. One of N-methylcarbamates and some nitro-or chloro-substituted derivatives were highly toxic against Piricularia oryzae. From the relationship between the chemical structure and the activity, it is supposed that the, reactivity, the permeability, the steric effect and the metabolic activation of the com pound are the responsible factors for the fungistatic activity. o-Phenylphenol is known to be highly toxic to some fungi. Many of its derivatives, es pecially chlorinated compounds, have been widely used not only for treating woods and fabrics against fungi, but also for protecting agricultural crops from some destructive patho gens. Informations on the syntheses, fungi cidal activity and toxicological properties of nitro-or chloro-substituted phenylphenols are scattered in literatures.'-" No systematic study on the relationship between their chem ical structure and fungicidal activity is reported.

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