As industrialization accelerates, the industrial sensor network environment becomes more complex. Hierarchical multi-cluster wireless sensing network topology is generally used due to large-scale industrial environments, harsh environments, and data overload impact. In industrial wireless sensor networks, the overload of some nodes may lead to the failure of the whole network, which is called cascading failure. This phenomenon has incalculable impact on industrial production. However, cascading failure models have mainly been studied for planar structures, and there is no cascading failure model for hierarchical topologies in industrial environments. Therefore, this paper built a cascading failure model for hierarchical industrial wireless sensor networks (IWSNs) for realistic industrial network topologies. By establishing an evaluation mechanism considering the efficiency of the network and the viability of nodes, the network communication efficiency that is not considered in the traditional evaluation mechanism is solved. In addition, aiming at the problem of network topology changes caused by node failure, dynamic load distribution methods (ADD, SLD) are used to improve network invulnerability. Theoretical analysis and experimental results show that the traditional allocation method (SMLD) does not apply in hierarchical topologies; when the general cluster head node capacity is moderate, increasing the capacity of single-hop cluster head nodes can prevent cascading failures more effectively.