Two-dimensional molybdenum disulfide (MoS) has attracted intense interest owing to its unique properties and promising biosensor applications. To develop effective biocompatible platforms, it is crucial to understand the interactions between MoS and biological molecules such as proteins, but little knowledge exists on the orientation and conformation of proteins on the MoS surface at the molecular level. In this work, the lysozyme adsorption on the MoS surface was studied by molecular dynamics simulations, wherein six different orientations were selected based on the different faces of lysozyme. Simulation results showed that lysozyme tends to adsorb on the MoS surface in an "end-on" orientation, indicating that orientations within this range are favorable for stable adsorption. The end-on orientation could be further categorized into "bottom end-on" and "top end-on" orientations. The driving forces responsible for the adsorption were dominated by van der Waals interactions and supplemented by electrostatic interactions. Further, the conformations of the lysozyme adsorbed on the MoS surface were basically preserved. This simulation study promotes the fundamental understanding of interactions between MoS and proteins and can guide the development of future biomedical applications of MoS.

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L-shaped NaV2O5 crystals with two straight arms of a nanowire assembly were controllably synthesized, and the (310) twin boundary was found to connect the nearly perpendicular arms to form an L-shaped structure.

Two novel polymers exhibiting metal-organic frameworks (MOFs) have been synthesized by the combination of a metal ion with a benzene-1,3,5-tricarboxylate ligand (BTC) and 1,10-phenanthroline (phen) under hydrothermal conditions. The first compound, poly[[(μ4-benzene-1,3,5-tricarboxylato-κ(4)O:O':O'':O''')(μ-hydroxido-κ(2)O:O)bis(1,10-phenanthroline-κ(2)N,N')dizinc(II)] 0.32-hydrate], {[Zn2(C9H3O6)(OH)(C12H8N2)2]·0.32H2O}n, denoted Zn-MOF, forms a two-dimensional network in which a binuclear Zn2 cluster serves as a 3-connecting node; the BTC trianion also acts as a 3-connecting centre. The overall topology is that of a 6(3) net. The phen ligands serve as appendages to the network and interdigitate with phen ligands belonging to adjacent parallel sheets. The second compound, poly[[(μ6-benzene-1,3,5-tricarboxylato-κ(7)O(1),O(1'):O(1):O(3):O(3'):O(5):O(5'))(μ3-hydroxido-κ(2)O:O:O)(1,10-phenanthroline-κ(2)N,N')dimanganese(II)] 1.26-hydrate], {[Mn2(C9H3O6)(OH)(C12H8N2)]·1.26H2O}n, denoted Mn-MOF, exists as a three-dimensional network in which an Mn4 cluster serves as a 6-connecting unit, while the BTC trianion again plays the role of a 3-connecting centre. The overall topology is that of the rutile net. Phen ligands act as appendages to the network and form the `S-shaped' packing mode.