Functional foods and drug industries have been rapidly developed.Natural products can be used as antioxidants, antimicrobial agents, and raw materials in pharmaceutical production (Dai & Mumper, 2010).Bioactive substances extracted from plants are widely used in medicine and food. Several methods have been developed for extracting, isolating, and purifying flavonoids and triterpenoids. However, more simple, efficient, and less expensive methods to produce large-scale high-quality products are urgently needed.Urtica fissa E. Pritz., Urticaceae is a perennial herb with 100-180cm of the whole plant height, transverse rhizome, tetra-prismatic, densely ciliate and puberulent, sparsely branched. It is a common shadeloving plant, featured by vigorous life, rapid growth, lax soil requirements, favoring of warm and wet characteristics. It usually grows in the hillside, roadside, or house half shade wet place (Weigend, 2006).Urtica is a relatively common wild plant. Its generic name comes from the Latin word urere, meaning "to rub or burn." Stems and leaves of urtica are covered with fine cilia, containing ingredients such as formic acid and histamine. There is an intense burning sensation when stunning (Bourgeois et al., 2016). Urtica is also widely distributed geographically. It grows in Eurasia, North America, and North Africa,
