Background: The purpose of this study was to analyze the effect of the meticulous nursing model on the treatment compliance and quality of life of patients with upper gastrointestinal bleeding (UGIB).Methods: A total of 108 UGIB patients treated in Linyi Central Hospital from October 2018 to October 2019 were selected as the study subjects, and were randomly divided into a research group and reference group, with 54 cases in each group. The reference group received conventional nursing while the research group received meticulous nursing on this basis to compare the clinical intervention effect and the impact on quality of life in the 2 groups of patients.Results: The Generic Quality of Life Inventory-74 (GQOLI-74) scores in the 2 groups of patients after intervention were significantly higher than those before intervention (P<0.001), and the score of the research group after intervention was significantly higher than that of the reference group (P<0.001). The Stanford Acute Stress Reaction Questionnaire (SASRQ) scores of the patients presented a trend opposite to GQOLI-74 (P<0.001). The number of fully satisfied cases in the research group was significantly higher than that in the reference group (P<0.05), while the number of dissatisfied cases was significantly lower than that in the reference group (P<0.05). The self-rating anxiety scale (SAS) scores in the 2 groups of patients after intervention were significantly lower than those before intervention (P<0.001), and the score of the research group after intervention was significantly lower than that of the reference group (P<0.001). The total clinical effective rate and treatment compliance of the research group were significantly higher than those of the reference group (P<0.05). Conclusions:The meticulous nursing model can effectively improve the quality of life of UGIB patients, reduce the psychological stress response, and improve clinical treatment compliance and nursing satisfaction with a definite effect, making it worthy of promotion and application.

Patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) were treated with immediate or sequential withdrawal after 5 days of systemic glucocorticoids. The effects of the two withdrawal methods on the prognosis of patients were compared at 30, 90, 180, and 360 days after discharge. A multicenter, randomized, double-blind, parallel-controlled, open-label study was conducted in the respiratory department of tertiary hospitals in Central China. Patients met inclusion criteria for AECOPD and needed to use systemic glucocorticoids. They were randomly assigned to immediate and sequential withdrawal groups at a 1:1 ratio. The study was completed in August 2020 and is registered at the China Clinical Trials Registry (Chictr.org) (ChiCTR1800018894). According to general data and clinical characteristics, there were no statistically significant differences between the 329 patients in the immediate withdrawal group and the 310 patients in the sequential withdrawal group (P &gt; 0.05). At the 30, 90, 180, and 360-days follow-up, the acute exacerbation frequency, rehospitalization rate, mortality, and intensive care unit (ICU) treatment rate were not significantly different between the immediate withdrawal group and sequential withdrawal group (P &gt; 0.05). The modified Medical Research Council (mMRC) and COPD assessment test (CAT) scores were also not significantly different between the two groups. At the 180- and 360-day follow-up, forced expiratory volume in 1 s (FEV1%) and peak expiratory flow (PEF) were not significantly different between the two groups (P &gt; 0.05). The time from discharge to first acute exacerbation was significantly lower in the immediate withdrawal group (46.12 days) than in sequential withdrawal group (49.02 days) (P &lt; 0.05). The time of stay in the hospital for the first time after discharge was not significantly different between the two groups (P &gt; 0.05). Adverse events were not significantly different between the immediate withdrawal group and sequential withdrawal group (P &lt; 0.05). Subgroup analysis was performed according to age, degree of disease, and relevant indicators. At the 30-day follow-up, the acute exacerbation frequency of patients with advanced age, high global strategy for chronic obstructive lung disease (GOLD), and high fractional exhaled nitric oxide was significantly higher in the immediate withdrawal group than in the sequential withdrawal group (P &lt; 0.05). In addition, according to receiver operating characteristic (ROC) curve analysis, the frequency of acute exacerbations at the 30-day follow-up was significantly higher in patients with age &gt; 63.5 years or GOLD &gt; 3 in the immediate withdrawal group than in the sequential withdrawal group, suggesting that the short-term efficacy was poor.

Objective. The purpose of the study was to investigate the therapeutic effect and nursing satisfaction of bedside nursing combined with detail nursing in the gastroenterology department. Methods. 112 patients with gastrointestinal diseases admitted to our hospital from November 2018 to November 2019 were selected as the study subjects and randomly divided into a research group (n = 56) and reference group (n = 56). The reference group received routine clinical nursing, while on this basis, the research group received bedside nursing combined with detail nursing. After that, the clinical nursing effects of the two groups were compared. Results. There were no significant differences in sex ratio, age, BMI, smoking history, drinking history, marital status, and disease types between the two groups ( P > 0.05 ). The VAS scores in the two groups after intervention were significantly lower than those before intervention ( P < 0.01 ), and the VAS scores in the research group after intervention were significantly lower than those in the reference group ( P < 0.01 ). The nursing ability, nursing skills, and nursing responsibility in the research group were significantly higher than those in the reference group ( P < 0.01 ). There were no significant differences between the two groups in the number of patients who were satisfied and needed improvement ( P > 0.05 ). Besides, the number of very satisfied cases in the research group was significantly higher than that in the reference group ( P < 0.05 ), and the number of unsatisfied cases was significantly lower than that in the reference group ( P < 0.05 ). The total incidence of clinical adverse events in the research group was significantly lower than that in the reference group ( P < 0.01 ). The gastrointestinal diseases related knowledge scores after intervention were significantly higher than those before intervention ( P < 0.01 ), and the gastrointestinal diseases related knowledge scores after intervention in the research group were significantly higher than those in the reference group ( P < 0.01 ). The GQOLI-74 scores after intervention in the two groups were significantly higher than those before intervention ( P < 0.01 ), and the GQOLI-74 scores after intervention in the research group were significantly higher than those in the reference group ( P < 0.01 ). Conclusion. The application of bedside nursing mode combined with detail nursing in gastrointestinal diseases can effectively reduce patients’ pains, as well as the incidence of clinical adverse events, and improve patients’ life quality, with definite curative effect, which is worthy of promotion and application.