These findings indicate that pirfenidone inhibits proliferation, migration, and collagen contraction of HTFs at nontoxic concentrations. A decrease in autocrine TGF-beta signaling may have a role in the effects of pirfenidone.

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We propose a novel method for quickly measuring the radon exhalation rate in open loop. We first obtain the temporal variation of radon concentration in the internal cell of the RAD7 by analyzing the work principle of RAD7. We then obtain the temporal variation of radon concentration in the ventilation-type accumulation chamber when the effects of leakage and back diffusion are neglected. This method uses the measured value before the radon concentration in the ventilation-type accumulation chamber reaches a steady state. The diameter of the air input tube to the ventilation-type accumulation is large enough to keep the differential pressure in the accumulation chamber and outdoors negligible. Short cycle time and large flow rate will be appropriate for reducing measurement error. Several radon exhalation rate measurements of the medium surface have been performed in the Radon Laboratory of the University of South China. The radon exhalation rates obtained by verification experiments are in good agreement with the reference value. This method can be applied to develop and improve the instruments for measuring radon exhalation rate.

This paper presents a process in which a radon monitor based on the electrostatic collection method is used to measure the (222)Rn and (220)Rn exhalation rates simultaneously and continuously employing a ventilation-type accumulation chamber. Generally, the radon exhalation rate can be measured by accumulation technique, but cannot be measured continuously. The advantage of this method using a ventilation-type accumulation chamber is that the radon exhalation rates can be measured continuously. Even though the environmental air is drawn into the chamber, the low atmospheric values of radon and thoron do not influence the measurement accuracy. The (222)Rn and (220)Rn exhalation rates error from the environmental air is less than 5% in this experiment.