The indicators of climate change in Central Europe, Hungary is showing a trend of decrease in rainfall, increase in temperature and especially extreme weather that is becoming more usual and unpredictable. The current study presents the application of the MIKE SHE model to examine the role of unsaturated soil settings and the effects of climate change on various hydrological parameters and water balance components. The input data has been provided by Lower-Tisza District Water Directorate. The one-at-atime method utilized in this study allows for the investigation of the impact of various input parameter combinations on the estimated values of different hydrological parameters and water balance components. The findings demonstrated that the level of detailedness of the soil as an input parameter significantly influences the results of the modelled groundwater circulation and therefore the dynamics of the water regime. According to the simulation results of the temperature increase, the water table can be regarded as the primary water supply that replenishes the streams. The simulation results show that the groundwater table and evapotranspiration are the two main driving forces in the Dong-ér catchment's water regime. These findings will be used as a reference for water resource management and irrigation infrastructure planning in the context of complex climate change contexts.