fMRI was used to determine the frontal, basal ganglia, and thalamic structures engaged by three facets of language generation: lexical status of generated items, the use of semantic vs. phonological information during language generation, and rate of generation. During fMRI, 21 neurologically normal subjects performed four tasks: generation of nonsense syllables given beginning and ending consonant blends, generation of words given a rhyming word, generation of words given a semantic category at a fast rate (matched to the rate of nonsense syllable generation), and generation of words given a semantic category at a slow rate (matched to the rate of generating of rhyming words). Components of a left pre-SMA-dorsal caudate nucleus-ventral anterior thalamic loop were active during word generation from rhyming or category cues but not during nonsense syllable generation. Findings indicate that this loop is involved in retrieving words from pre-existing lexical stores. Relatively diffuse activity in the right basal ganglia (caudate nucleus and putamen) also was found during word-generation tasks but not during nonsense syllable generation. Given the relative absence of right frontal activity during the word generation tasks, we suggest that the right basal ganglia activity serves to suppress right frontal activity, preventing right frontal structures from interfering with language production. Current findings establish roles for the left and the right basal ganglia in word generation. Hypotheses are discussed for future research to help refine our understanding of basal ganglia functions in language generation.
The Paced Auditory Serial Addition Test (PASAT; Gronwall, 1977; Gronwall & Sampson, 1974) is a measure of attention and information processing speed sensitive to mild traumatic brain injury (MTBI), but it is aversive and inappropriate for many other neurologically impaired patients. This study examines a simpler, less aversive visual analog of the PASAT (the Paced Visual Serial Addition Test; PVSAT) in a sample of 74 college students (26 with a history of TBI). Results indicated that the PVSAT is moderately correlated with and less difficult than the PASAT. Both tests had identical relations to other measures of attention. Neither the PVSAT, PASAT, nor the other attentional measures differentiated participants with MTBI from normal controls in a college population. This preliminary study thus demonstrates the comparability of the two tests and presents the PVSAT as a viable alternative to the PASAT. Directions for future research and applications of these findings are discussed.
To refocus awareness on the original mandate of the Health Insurance Portability and Accountability Act (HIPPA) regulations, this article will review record keeping requirements and examine patient-doctor and interdisciplinary communication as a way to improve the health care consumer's trust in the privacy of their personal information while facilitating integrated and fluid health care delivery systems. The HIPPA rules especially important in medical settings are discussed with a special emphasis on issues confronting psychologists who practice outside of medical institutions and hospitals. The article also examines important implications for practice activities when psychologists attend patients who are hospitalized.
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