BackgroundAdvances in coronary artery surgery have reduced patient morbidity and mortality. Nevertheless, patients still have to face physical, psychological, and social problems after discharge from hospital.ObjectivesThe objective of this study was to determine the efficacy of Pender’s health promotion model in predicting cardiac surgery patients’ lifestyles in Iran.MethodsThis cross-sectional study comprised 220 patients who had undergone coronary artery bypass graft (CABG) surgery in Mazandaran province (Iran) in 2015. The subjects were selected using a simple random sampling method. The data were collected via (1) the health-promoting lifestyle profile II (HPLP II) and (2) a self-designed questionnaire that included two main sections: demographic characteristics and questions based on the health-promoting model constructs.ResultsSpiritual growth (28.77 ± 5.03) and physical activity (15.79 ± 5.08) had the highest and lowest scores in the HPLP II dimensions, respectively. All the health promotion model variables were significant predictors of health-promoting behaviors and explained 69% of the variance in health-promoting behaviors. Three significant predictors were estimated using regression coefficients: behavioral feelings (β = 0.390, P < 0.001), perceived benefits (β = 0.209, P < 0.001), and commitment to a plan of action (β = 0.347, P < 0.001).ConclusionsAccording to the results of the study, health-promoting model-based self-care behaviors can help identify and predict cardiac surgery patients’ lifestyles in Iran. This pattern can be used as a framework for discharge planning and the implementation of educational interventions to improve the lifestyles of CABG patients.