Aims  The aim of this study was to determine the contemporary use of reperfusion therapy in the European Society of Cardiology (ESC) member and affiliated countries and adherence to ESC clinical practice guidelines in patients with ST-elevation myocardial infarction (STEMI). Methods and results  Prospective cohort (EURObservational Research Programme STEMI Registry) of hospitalized STEMI patients with symptom onset <24 h in 196 centres across 29 countries. A total of 11 462 patients were enrolled, for whom primary percutaneous coronary intervention (PCI) (total cohort frequency: 72.2%, country frequency range 0–100%), fibrinolysis (18.8%; 0–100%), and no reperfusion therapy (9.0%; 0–75%) were performed. Corresponding in-hospital mortality rates from any cause were 3.1%, 4.4%, and 14.1% and overall mortality was 4.4% (country range 2.5–5.9%). Achievement of quality indicators for reperfusion was reported for 92.7% (region range 84.8–97.5%) for the performance of reperfusion therapy of all patients with STEMI <12 h and 54.4% (region range 37.1–70.1%) for timely reperfusion. Conclusions  The use of reperfusion therapy for STEMI in the ESC member and affiliated countries was high. Primary PCI was the most frequently used treatment and associated total in-hospital mortality was below 5%. However, there was geographic variation in the use of primary PCI, which was associated with differences in in-hospital mortality.

IntroductionAcute coronary syndrome (ACS), including myocardial infarction (MI), is a costly condition and the leading cause of mortality in both women and men throughout the world. 1,2 The incidence of MI is constantly increasing worldwide, mostly due to population aging and sedentary lifestyle. 3,4 Many risk factors, directly or indirectly, may affect the outcomes of patients with MI. 5 The outcomes disparity between women and men after acute myocardial infarction (AMI) has been reported frequently but with a wide variety in different ethnic and demographic groups. [5][6][7][8][9] The reasons for the sex-based differences have not been clear yet, though, the known risk factors for MI such as diabetes mellitus (DM), hypercholesterolemia, and hypertension (HTN) in women are more frequent than men. 10-12 After adjustment for possible confounders such as age and other risk factors, some researchers found no differences in the mortality rate between men and

Background:The Kermanshah Acute Coronary Syndrome (KACS) Registry, funded by Kermanshah University of Medical Sciences (KUMS). Currently, the patients diagnosed by ST-elevation myocardial infarction (STEMI), are recruited. The registry is aimed to be expanded to include all patients with the diagnosis of ACS including STEMI, in 2022 subject to the success of current project. Methods:In an ongoing cohort study, started July 2016, patients with a diagnosis of STEMI, being ≥18 years old, are recruited. The study proposal has been approved by KUMS' Ethics committee and European Observational Registry Program (EORP). The baseline data include patients' characteristics, presenting symptoms, past medical history, clinical findings, medical procedures and paramedical tests are collected via patient interview and using a check list and questionnaire developed by EORP. The patients will be followed up annually for a minimum of two years. Results:To date 2100 patients with STEMI have been recruited. Data on 220 variables for each participant has been collected. The first year follow up finished July 2018. We are analysing the results. An abstract entitled "Is any sex-specific difference in diabetes adverse effects on the outcomes of patients with myocardial infarction?" was presented at the 20th Asia Pacific Diabetes Conference in Australia (2018).The results gradually will be published. Conclusions:The data in this registry will provide detailed epidemiologic characteristics and a list of risk factors, clinical features, therapeutic approaches provided for patients and their complications. It creates the possibility of investigation of such patients for next two years after their STEMI. BackgroundMyocardial infarction (MI) refers to the presence of evidence of tissue necrosis associated with acute ischemic heart disease [1]. STsegment elevation myocardial infarction (STEMI) is the term used to describe a classic heart attack that is the most deadly sub-class of MI, and accounting for more than 35% of MI cases. The most common cause of myocardial infarction is coronary plaque rupture

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Analyzing child mortality, an important indicator of health and development of countries, can help policymakers to develop health programs that resulted in improving Childs’s health. Recognizing the causes of in-hospital deaths also assists health caregivers to revise their medical services. The aim of this study was to explore the causes of death in the largest hospital in western Iran. This retrospective descriptiveanalytical study was conducted in Imam Reza Hospital (IRH) in Kermanshah, data including demographic characteristics (e.g., age), medical information, and causes of death of patients aged ≤18 years, from April 2012 to March 2017 were collected using a checklist. The causes of mortalities were categorized based on the International Coding of Diseases (ICD, Version 10). Using logistic regression, Chi-square, and Cramer's V test in SPSS, the relationships between the outcome and predicting variables were assessed. The results showed 1113 deaths among 21,247 people≤, 18 years people admitted to IRH for five years. About 55% were female and 74% neonate, with a dropping trend from 2011 (4.62%) to 2016 (4.00%). Medical records, mostly, used a variety of usual medical terms for the causes of death, rather than using ICD10 categories. Data were analyzed after alternating medical terms and re-coding data using ICD10. Respiratory system diseases by 34% (dominancy of hyaline membrane diseases), infectious diseases by 28% (leading by sepsis), and diseases of the blood by 13% (mostly disseminated intravascular coagulation (DIC)), respectively, were the most common causes of death. Age was the most important associated factor for all-cause mortality associated with infectious diseases and respiratory system diseases (P=0.01). Having a significant number of neonatal mortality, paying more attention to the neonatal, prenatal, and antenatal care is recommended. In addition, the fatality of infectious diseases is concerning and needs paying serious attention to the health care system.