Menopause known as change of life, Perimenopause comprise a half or a third of a women's life, particularly in developing countries, which troublesome symptoms. Empowerment during the menopause can improve women's adaptation to menopausal symptoms. This study Aims to compare adaptational methods among medical and nonmedical personnel regarding transitional menopausal symptoms. Setting of this study was outpatient clinics of Sedfa central hospital & maternal &child health care center (MCH) at Sedfa district in Assiut governorate, Egypt. A descriptive, comparative Design was used in this study. A Purposive sample of 140 participants (70 women from medical personnel and 70 women from non-medical personnel) A tool used was interviewing questionnaire. Results of this study revealed that the most common transitional symptoms both medical and non-medical personnel complained of were sleeping disturbance followed by hot flushes. Adaptational method to sleep disturbances was similar but with large percentage among medical than non-medical personnel in a form of being physically active. Adaptational methods to hot flushes was similar but with large percentage among medical than non-medical participants in a form of trying to avoid things that may trigger the symptoms. This study concluded that medical participants were practiced adaptational methods more than non-medical participants in some transitional menopausal symptoms, while these adaptational methods were nearly similar in others This study Recommended to increase women's awareness of transitional menopausal symptoms and methods of adaptation.