Dear Editor, The most common genomic abnormality in Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs) is a functional V617F mutation in the Janus kinase 2 (JAK2) kinase-like structural domain [1,2]. Although chromosomal translocation involving JAK2 is rare, it has been reported in hematological malignancies [3]. Because of similar clinical features, experts advocate that all rare JAK2 rearrangement cases should be classified into the same category [4]. We report a case of MPN with BCR-JAK2 and BCR-PPP1R32 rearrangements, showing t(9;22; 11)(p24;q11.2;q13). To our knowledge, this is the first report of PPP1R32 as a novel fusion partner of BCR. Written informed consent was obtained from the patient for publication of this case report and accompanying images. This case study was approved by the Institutional Review Board of Army Medical University, Chongqing, China (No.2021-219).A 56-year-old man was admitted to our outpatient clinic in March 2020 for fatigue and left upper abdominal pain. Peripheral blood examination indicated a white blood cell (WBC) count of 178.1 × 10 9 /L (25.0% neutrophils, 4.0% lymphocytes, 1.0% monocytes, 4.0% eosinophils, 0% basophils, 18.0% late granu-

Background: In abdominal magnetic resonance imaging (MRI), the late hepatic arterial phase is particularly important for the diagnosis of hepatocellular carcinoma (HCC). However, poor patient compliance with breath-hold imaging acquisition protocols and the administration of the liver-specific contrast agent gadolinium ethoxybenzyl-diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) increases the motion artifacts that degrade the quality of the images making it more difficult to interpret the images. Objective: This study aimed to evaluate the role of adaptive respiratory training in improving the quality of the MRI by reducing the motion artifacts and improving the signal intensity from the regions of interest (ROI) in the late hepatic arterial phase. Methods: A total of 120 patients who underwent an abdominal MRI between 2021 to 2022 to assess for the liver disease were included in the study. These patients were divided into two groups: the experimental group and the control group. The patients in the experimental group received adaptive training. The incidence of motion artifacts and the signal intensity in the late hepatic arterial phase within the abdominal aorta, hepatic artery, splenic artery, and hepatic parenchyma between the experimental group and the control group were compared. Results: The incidence of motion artifacts in the experimental group was significantly reduced by 28.3% (p = 0.001, Chi-square value = 12.079). In the late hepatic arterial phase, the signal intensity of the abdominal aorta, the hepatic artery, the splenic artery, and the hepatic parenchyma increased by 7.3%, 27.4%, 29.5%, and 6.9%, respectively. Conclusion: Adaptive respiratory training reduced the incidence of motion artifacts and improved the signal intensity for various ROI. The improved image quality could potentially facilitate image interpretation and reduce the number of repeat MRI scans.

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