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In the title compound [systematic name: 2-hy­droxy-N-(5-nitro-1,3-thia­zol-2-yl)benzamide pyridine monosolvate], C10H7N3O4S·C5H5N, the dihedral angle between the pyridine and benzamide rings is 80.55 (7)°. An intamolecular O—H⋯N hydrogen bond occurs in the tizoxanide. In the crystal, the components are linked by an O–H⋯N hydrogen bond, forming a zigzag chain along the c axis. Aromatic π–π inter­actions between inversion-related pyridine rings [centroid–centroid distance = 3.803 (6) Å] are also observed.