Molybdenum disulfide (MoS2) ultrathin nanosheets with enlarged interlayer spacing and defects enables the structure-enhanced removal of Cr(vi), in which the synergistic effects of adsorption and reduction not only captured Cr(vi) from aqueous solutions, but also alleviated the toxicity of chromium to some degree.

Background: Pelvic organ prolapse (POP) is a common pathology in the female population. Sacrospinous ligament fixation (SSLF) is one of the traditional transvaginal procedures for POP and high sacrospinous ligament fixation (h-SSLF) optimizes it using an antegrade reusable suturing device (ARSD-Ney). Previous studies on h-SSLF have focused on the correction of anatomical positions, with less assessment of patients' function, quality of life and complications. In this study, we evaluated post-operative complications, function, and quality-of-life after h-SSLF to confirm the safety and effectiveness of it. Methods: This was a retrospective cohort study that included 71 patients between 2018 and 2021: 50 patients for h-SSLF and 21 patients for laparoscopic sacrocolpopexy (LSC) according to patient age and background, POP-Q stage, patient preference, and so on. A clinical evaluation took place before surgery and was repeated at 6 and 12 months postoperatively. Intra-and post-operative complications and anatomical results were recorded. Patients completed self-administered questionnaires for functional pelvic problems [Pelvic Floor Disability Index-20 (PFDI-20)], quality of life [Pelvic Floor Impact Questionnaire-7 (PFIQ-7)], and sexual function [Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire-12 (PISQ-12)] at each medical visit.Results: Patients in both h-SSLF and LSC groups were similar in terms of demographic characteristics except for surgery time (86.04±28.70 vs. 153.19±54.88, P<0.05), postoperative indwelling catheter time (3.88±1.65 vs. 4.90±1.84, P<0.05), and hospital stay (8.94±2.38 vs. 10.57±2.06, P<0.05). There were no statistically significant differences between the 2 groups in scores of PFDI-20, PFIQ-7, and PISQ-12 at preand post-operative 6 and 12 months (P>0.05). Functional pelvic problems (PFDI-20 scores) and their impact on patients' quality of life (PFIQ-7 scores) significantly improved at 6 and 12 months postoperatively (P<0.05).Improvements in sexual activity were noted at 6 and 12 months postoperatively (P<0.05).Conclusions: This retrospective cohort study confirmed the positive results of h-SSLF in terms of improvement in function and quality of life following treatment for pelvic organ prolapse.

In recent years, the number of cases of heart disease has been greatly increasing, and heart disease is associated with a high mortality rate. Moreover, with the development of technologies, some advanced types of equipment were invented to help patients measure health conditions at home and predict the risks of having heart disease. The research aims to find the accuracy of selfmeasurable physical health indicators compared to all indicators measured by healthcare providers in predicting heart disease using five machine learning models. Five models were used to predict heart disease, including Logistics Regression, K Nearest Neighbors, Support Vector Model, Decision tree, and Random Forest. The database used for the research contains 13 types of health test results and the risks of having heart disease for 303 patients. All matrices consisted of all 13 test results, while the home matrices included 6 results that could test at home. After constructing five models for both the home matrices and all matrices, the accuracy score and false negative rate were computed for every five models. The results showed all matrices had higher accuracy scores than home matrices in all five models. The false negative rates were lower or equal for all matrices than home matrices for five machine learning models. The conclusion was drawn from the results that home-measured physical health indicators were less accurate than all physical indicators in predicting patients' risk for heart disease. Therefore, without the future development of home-testable indicators, all physical health indicators are preferred in measuring the risk for heart diseases.

Objective: We aimed to investigate whether ovarian cancer and cancer-related fatigue are associated with a sudden loss of ovarian dysfunction.Methods: In total, we retrospectively analyzed 211 survivors of ovarian carcinoma from the First Affiliated Hospital of Soochow University between January 2015 and January 2020. Fatigue was measured with the Cancer Fatigue Scale (CFS). Single and multiple linear regression were used to determine statistical differences.Results: Fatigue was reported in 206 of all completed questionnaires. Patients who had a menstrual period prior to treatment had a higher fatigue score. The CRF score was highest during the first two years after treatment and gradually decreased over time. Patients with sleep disorders became fatigued more easily. We identified a negative correlation between hemoglobin and CRF. There were no significant correlations between CRF, the number of chemotherapy cycles, the type of chemotherapy regimen, or the pathological subtype of ovarian cancer.Conclusion: CRF is common in ovarian cancer patients and improve CRF are important for improving the quality of life. The fatigue experienced by patients with ovarian cancer may be related to the deprivation of sex hormones. It may be prudent to add such hormones to the treatment regimen in order to improve CRF.