Highlights d Human ACE2 knockin mice were generated by using CRISPR/Cas9 technology d SARS-CoV-2 leads to robust replication in lung, trachea, and brain d SARS-CoV-2 causes interstitial pneumonia and elevated cytokine in aged hACE2 mice d High dose of SARS-CoV-2 can establish infection via intragastric route in hACE2 mice
This study outlined the epidemiologic data of invasive yeast infections and highlighted the need for continuous monitoring of azole resistances among C. glabrata and C. tropicalis isolates in Beijing.
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