Aim: This study was conducted to investigate the effects of oral care provided suction toothbrush, suction sponge stick and sponge stick in patients receiving mechanical ventilation. Material and method:The study was conducted as a quasi-experimental study. Thirty patients who were over 18 years of age and receiving mechanical ventilation comprised the study sample. The patients who met the inclusion criteria were divided into three groups: the suction toothbrush group, the suction sponge stick group and the sponge stick group. The patients in the three groups were provided oral care by the researcher twice a day at 12-hour intervals for 5 days. To collect the data, the socio-demographic characteristics form, the patient follow-up form, the Oral Assessment Follow-up Form and the microbiological follow-up form were used.