It was observed that the groups PTX2, RC, R25, UC L25 25/0.06, and WO Primary presented greater cyclic fracture resistance than the other groups (P< 0.001).

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Objective: To report two cases in which conventional endodontic therapy resulted in clinical success without the need for further corrective surgery. Case report: The first case reports a 21-year-old patient who sought dental care for orthodontic reasons. Panoramic radiograph revealed a large radiolucent area in the periapical region of teeth #12 , 11 , 21 , 22 and 23. Treatment was limited to endodontic therapy which consisted of pulpectomy , emptying the septic content, biomechanical preparation and dressing. In the second session , the root canal system of all 5 teeth were filled. Radiographic control after two and five years showed complete repair of the radiolucent area and areas of bone formation. The second case reports a 84-year-old, diabetic patient who sought dental care for prosthodontic reasons. Intraoral examination revealed expansion of cortical bone in the lower anterior region. Panoramic radiograph revealed extensive radiolucent area in teeth #32 , 31 , 41 , 42 and 43. Treatment consisted of conservative endodontic treatment , without the further need for surgery similar to the first case. Radiographic control after one year showed decreased radiolucency and bone healing. Conclusion: Surgery is not always recommended for cases of large periapical lesions and the clinical and radiographic follow-ups are of paramount importance for treatment.