Intacs implantation with transepithelial CXL is effective in eyes with keratoconus. Collagen cross-linking has an additive effect on Intacs implantation in these eyes and may be considered as an enhancement/stabilizing procedure.

PurposeTo report the successful use of tofacitinib in the treatment of refractory uveitis and scleritis.ObservationsTwo patients, one with scleritis and another with anterior and intermediate uveitis, presented with refractory disease after failure of multiple steroid-sparing therapies. Treatment with tofacitinib led to durable resolution of uveitis and scleritis.Conclusions and importanceTofacitinib is a potential novel treatment option for refractory, noninfectious inflammatory eye disease.