The 2010 Malawi Demographic and Health Survey (MDHS) is a large, nationally representative sample survey conducted by the National Statistical Office (NSO). The 2010 MDHS covered a total of 27,000 households, involving 24,000 female and 7,000 male respondents. The primary objective of the 2010 MDHS is to provide up-to-date information for policymakers, planners, researchers, and programme managers on fertility levels, nuptiality, fertility preferences, knowledge and use of family planning methods, breastfeeding practices, nutritional status of mothers and children, childhood illnesses and mortality, use of maternal and child health services, malaria, maternal mortality, and HIV and AIDS-related knowledge and behaviour. The survey also provides the anaemia status of women age 15-49 and children age 6-59 months. There have been four rounds of the MDHS conducted-in 1992,2000,2004, and 2010. This preliminary report presents tables showing the status and trends for a selected number of indicators current fertility, current use of contraception, vaccinations, nutritional status of children, and knowledge of HIV and AIDS among others.