Since ministry of education has targeted "Golden Courses" as one key construction project, a new round of reform for teaching model is looming. Due to unique advantages of the online to offline blended teaching model, it is increasingly being used to practice. This paper comparatively analyzes characteristic of current class and superiority of online to offline (O2O) blended teaching model. Based on active learning and higer-order teaching goal, application of the online to offline blended teaching for talent cultivating is deeply explored. Moreover, an improved design of O2O blended teaching, which can be used for reference is proposed.