BackgroundNearly 40% of colorectal cancer (CRC) recurs within 2 years after resection of primary tumor. Imaging with fluorine-18-fluorodeoxyglucose (l8F-FDG) positron emission tomography/computed tomography (PET/CT) is the most recent modality and often applied for the evaluation of metastatic spread during the follow-up period. Our goal was to study the diagnostic importance of 18F-FDG-PET/CT data of maximum standardized uptake value (SUVmax), total lesion glycolysis (TLG) and the difference of SUVmax on dual-time imaging in CRC.Patients and methodsWe examined the SUVmax value of lesions on control or restaging 18F-FDG-PET/CT of 53 CRC patients. All lesions with increased SUVmax values were confirmed by colonoscopy or histopathology. We compared PET/CT results with conventional imaging modalities (CT, MRI) and tumor markers (carbohydrate antigen 19-9 [Ca 19-9], carcinoembryonic antigen [CEA]).ResultsMean SUVmax was 6.9 ± 5.6 in benign group, 12.7 ± 6.1 in malignant group. Mean TLG values of malignant group and benign group were 401 and 148, respectively. 18F-FDG-PET/CT was truely positive in 48% of patients with normal Ca 19-9 or CEA levels and truely negative in 10% of cases with elevated Ca 19-9 or CEA. CT or MRI detected suspicious malignancy in 32% of the patients and 18F-FDG-PET/CT was truely negative in 35% of these cases. We found the most important and striking statistical difference of TLG value between the groups with benign and recurrent disease.ConclusionsAlthough SUVmax is a strong metabolic parameter (p = 0.008), TLG seems to be the best predictor in recurrence of CRC (p = 0.001); both are increasing the specificity of 18F-FDG-PET/CT.

Objectives YouTube is one of the most popular online sources of information for patients. The purpose of the study is to analyze the quality of YouTube videos about the most commonly applied radionuclide treatments. Method Related radionuclide therapy videos were searched on YouTube in October 2021. The quality of the videos was assessed by using the Journal of the American Medical Association (JAMA) benchmark criteria, the DISCERN Scale and the Global Quality Scale (GQS). Results A total of 473 videos were assessed and 270 were included in the study according to inclusion and exclusion criteria. According to the GQS score, videos were categorized as high-quality (n:63, 23.33%), intermediate quality (n:118, 43.70%) and low-quality (n:89, 32.96 %) groups. The findings of our study showed that the highest number of video views and comments were in the low-quality group. In addition; the number of video likes, views and comments were the lowest in the high-quality video group. The most viewed and commented as well as most liked videos and the videos of highest video power index scores were nonphysician sourced videos. The most quality videos were the physician-sourced videos in terms of JAMA, DISCERN and GQS scores. Conclusion Although high-quality videos about radionuclide treatments on YouTube may enlighten and motivate patients positively; it should be kept in mind that improper information may also be uploaded to this platform. Under the guidance of the European Association of Nuclear Medicine, it is necessary to generate an official video in English with multilingual subtitles.

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