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This research investigates the heat and mass transfer in 3-D MHD radiative flow of water based hybrid nanofluid over an extending sheet by employing the strength of numerical computing based Lobatto IIIA method. Nanoparticles of aluminum oxide (Al2O3) and silver (Ag) are being used with water (H2O) as base fluid. By considering the heat transfer phenomenon due to thermal radiation effects. The physical flow problem is then modeled into set of PDEs, which are then transmuted into equivalent set of nonlinear ODEs by utilizing the appropriate similarity transformations. The system of ODEs is solved by the computational strength of Lobatto IIIA method to get the various graphical and numerical results for analyzing the impact of various physical constraints on velocity and thermal profiles. Additionally, the heat transfers and skin friction analysis for the fluid flow dynamics is also investigated. The relative errors up to the accuracy level of 1e-15, established the worth and reliability of the computational technique. It is observed that heat transfer rate increases with the increase in magnetic effect, Biot number and rotation parameter.

Background: Mathematical modeling of vector-borne diseases and forecasting of epidemics outbreak are global challenges and big point of concern worldwide. The outbreaks depend on different social and demographic factors based on human mobility structured with the help of mathematical models for vector-borne disease transmission. In Dec 2019, an infectious disease is known as “coronavirus” (officially declared as COVID-19 by WHO) emerged in Wuhan (Capital city of Hubei, China) and spread quickly to all over the china with over 50,000 cases including more than 1000 death within a short period of one month. Multimodal modeling of robust dynamics system is a complex, challenging and fast growing area of the research. Objectives: The main objective of this proposed hybrid computing technique are as follows: The innovative design of the NAR-RBFs neural network paradigm is designed to construct the SITR epidemic differential equation (DE) model to ascertain the different features of the spread of COVID-19. The new set of transformations is introduced for nonlinear input to achieve with a higher level of accuracy, stability, and convergence analysis. Methods: Multimodal modeling of robust dynamics system is a complex, challenging and fast growing area of the research. In this research bimodal spread of COVID-19 is investigated with hybrid model based on nonlinear autoregressive with radial base function (NAR-RBFs) neural network for SITR model. Chaotic and stochastic data of the pandemic. A new class of transformation is presented for the system of ordinary differential equation (ODE) for fast convergence and improvement of desired accuracy level. The proposed transformations convert local optimum values to global values before implementation of bimodal paradigm. Results: This suggested NAR-RBFs model is investigated for the bi-module nature of SITR model with additional feature of fragility in modeling of stochastic variation ability for different cases and scenarios with constraints variation. Best agreement of the proposed bimodal paradigm with outstanding numerical solver is confirmed based on statistical results calculated from MSE, RMSE and MAPE with accuracy level based on mean square error up to 1E-25, which further validates the stability and consistence of bimodal proposed model. Conclusions: This computational technique is shown extraordinary results in terms of accuracy and convergence. The outcomes of this study will be useful in forecasting the progression of COVID-19, the influence of several deciding parameters overspread of COVID-19 and can help for planning, monitoring as well as preventing the spread of COVID-19.