The wind-induced performance response of large-span truss curved roofs is extremely complex and changes obviously under wind load. This paper has taken the large-span steel roof of Liu Zhaike highway toll station as an example to analyze by both numerical simulations and field tests of responses of the steel canopy under wind load. In this case, simulated analysis results using finite element software were calibrated and verified by the field test results. In addition, a new method of large structure field testing was proposed which obtained the internal force and displacement of the canopy structure. Moreover, this paper analyzed and determined the actual stress state of the rectangular pipe truss. Finally, the safety condition of the roof was evaluated based on the monitoring data and the simulation of the finite element model. And the analysis methods provides references for similar engineering field tests, as well as guidance for the operation and maintenance for this project.