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A859 benefits were discounted at a fixed annual rate of 3%. Results: In base-case analysis, TST followed by QFT strategy was the most cost-effective among mental patients. No screening and CXR strategies were less cost-effective. Cost-effectiveness was sensitive to LTBI rate and BCG vaccination rate among non-smokers. No screening strategy was more cost-effective than TST followed by QFT strategy at the willingness to pay level of $US 100,000/QALY gained when LTBI rate among non-smokers was less than 0.10. The QFT strategy was more cost-effective than TST followed by QFT strategy at the willingness to pay level of $US 100,000/QALY gained when BCG vaccination rate among non-smokers was less than 0.18. ConClusions: TB screening using an IGRA for mental patients is recommended on the basis of the cost-effectiveness, especially with tobacco smoking. This suggests that further supporting tobacco cessation intervention for smoking mental patients is beneficial to control TB. PMD15 HealtH econoMic evaluation of WatcHMantM left atrial aPPenDage closure (laac) Device vesus long-terM Warfarin tHeraPy in Patients WitH atrial fibrillation (af) in cHina