Rutaecarpine is an indolopyridoquinazolinone alkaloid isolated from Evodia rutaecarpa and related herbs, which has shown a variety of intriguing biological properties such as anti-thrombotic, anticancer, anti-inflammatory and analgesic, anti-obesity and thermoregulatory, vasorelaxing activity, as well as effects on the cardiovascular and endocrine systems. Recent progress in the studies on the isolation, synthesis, structure-activity relationship studies, biological activities and metabolism of rutaecarpine are reviewed.

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Most of the information available is based on observations made during commercial production of titanium components in the aerospace industry. Titanium alloys are used widely where the strength-to-weight ratio and corrosion resistance are of the utmost importance. These alloys have been classified as 'difficult-to-machine' materials. Research work has been carried out to determine the temperature field in the cutting zone of titanium alloy Ti6Al4V during high speed milling. In the present work, uncoated cemented carbide tools were used in the milling of Ti6Al4V. The experiments were carried out under dry cutting conditions. Tests were performed on a Mikron 18000 rpm high speed machining centre and temperatures were measured using the implanted workpiece thermocouple techniques.

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