Background. With every passing year, the morta-lity from cardiovascular diseases is increasing. One of the treatment methods is X-ray endovascular plasty and coronary sten-ting. However, the X-ray endovascular plasty by itself inevitably causes at least minimal impairment of coronary vessels and myocardium. The study aimed at the assessment of small electrocardiography changes using an original method of scaling immediately after the procedure of coronary stenting. Materials and methods. The study was performed in 2020 based on ES “Institute of Heart of MH of Ukraine”. Twenty-three patients were examined before coronary stenting. This investigation included pair measurements, particularly electrocardiography registration within 3 min before and after (in several hours) the surgical intervention. The examination was performed using hardware-software complex “Cardio+P”. Total of 23 pairs of electrocardiograms were analyzed. Two hundred and forty primary and measurement parameters of electrocardiography were analyzed in each electrocardiogram. Results. The results of electrocardiographic investigation allowed determining a subgroup with significant myocardium impairments. This subgroup included the patients elder compared to the rest patients. In this subgroup, the average number of stents was higher and the patients demonstrated worsened index of the psychoemotional condition along with the electrocardiogram changes.