A high frequency of ICH due to late VKDB was reported in Egyptian infants aged two to 24 weeks, with poorer outcomes than international studies. A national survey is required to evaluate the timing and protective value of a second booster vitamin K dose to reduce ICH, especially in high-risk patients in this age group.
Our study of patients aged 12-13 months supported the theory of autonomic dysfunction in BHSs. The ECG findings, especially in patients with prolonged or frequent spells, need to be studied further to evaluate the risk of life-threatening events. Iron deficiency may play a role in autonomic dysfunction in patients with BHSs.
Idiopathic Epilepsy in children is associated with several comorbidities. Tics and other deviant behaviors are some of them which could negatively impact the family quality of life. The current study aimed at comparing quality of life and behavioral test results in children with epilepsy and tics versus those with epilepsy only.
Patients and Methods
Sixty patients with idiopathic epilepsy aged from 4 to 18 years participated in the current study. Group I included 30 patients with idiopathic epilepsy and tic disorders aged 10.1+/-3.2 years and group II 30 with epilepsy only aged 10.1+/-3.1 years. The Arabic version of the Pediatric quality of life inventory 4.0 (PedsQLTM 4.0), the Arabic translation of the Child Behavior Checklist (CBCL) scores were used and Conner’s parent rating scale were used. The results were compared between the 2 participating groups.
Results
Group I patients had worse total quality of life scores for both the child’s and parent’s scores compared to group II patients (p<0.05). CBCL scores were significantly higher in group I regarding most of the internalizing and externalizing domains yet the total score was non-significantly higher in group I compared to group II (p=0.05). Group I patients had higher total Conner’s score compared to group II; (p=0.045). Furthermore, those with ADHD in group I was 70% compared to 50% in group II.
Conclusion
Tic disorders in the context of idiopathic epilepsy should be addressed seriously as they are associated with other behavioral defects that require intervention to achieve better quality of life.
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