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Reporting of new or unexpected adverse drug reactions of medicines that are subject to additional monitoring (“black triangle” label), such as the antipsychotic drug cariprazine, is of paramount importance to improve pharmacotherapy safety.

The activity concentrations of (40)K, (238)U, (232)Th and (137)Cs have been measured using a gamma spectrometric method in different samples from the environment of two mountains in Serbia (altitude 1000-1100 m), during the period 2002-2007. The mountains Maljen and Tara (popular tourist destinations) are near Belgrade. On mountain Maljen, samples were taken at 4 different altitudes (200 m, 650 m, 1000 m and 1100 m), and on mountain Tara at altitudes of 1000 m and 1100 m. On mountain Maljen it was found that the level of (137)Cs activity increased with altitude in samples of soil, grass, hay and cow, sheep and goat milk. On the contrary, (40)K activity decreased with altitude in samples of soil, grass and hay. The highest activity concentrations of (137)Cs were found in bioindicators: sheep meat, venison, wild boar meat, moss and mushrooms. These results indicate that (137)Cs is present in mountain region of Serbia even 20 years after the nuclear accident in Chernobyl. Deposition of (137)Cs was almost two times higher on the Maljen mountain compared to Tara mountain. An average annual dose arising from (137)Cs was 7.4 microSv due to ingestion of cow milk and 6.3 microSv due to ingestion of mushrooms at the Maljen mountain.

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