Background In contrast with the setting of acute myocardial infarction, there are limited data regarding the impact of diabetes mellitus on clinical outcomes in contemporary cohorts of patients with chronic coronary syndromes. We aimed to investigate the prevalence and prognostic impact of diabetes according to geographical regions and ethnicity. Methods and results CLARIFY is an observational registry of patients with chronic coronary syndromes, enrolled across 45 countries in Europe, Asia, America, Middle East, Australia, and Africa in 2009–2010, and followed up yearly for 5 years. Chronic coronary syndromes were defined by ≥1 of the following criteria: prior myocardial infarction, evidence of coronary stenosis >50%, proven symptomatic myocardial ischaemia, or prior revascularization procedure. Among 32 694 patients, 9502 (29%) had diabetes, with a regional prevalence ranging from below 20% in Northern Europe to ∼60% in the Gulf countries. In a multivariable-adjusted Cox proportional hazards model, diabetes was associated with increased risks for the primary outcome (cardiovascular death, myocardial infarction, or stroke) with an adjusted hazard ratio of 1.28 (95% confidence interval 1.18, 1.39) and for all secondary outcomes (all-cause and cardiovascular mortality, myocardial infarction, stroke, heart failure, and coronary revascularization). Differences on outcomes according to geography and ethnicity were modest. Conclusion In patients with chronic coronary syndromes, diabetes is independently associated with mortality and cardiovascular events, including heart failure, which is not accounted by demographics, prior medical history, left ventricular ejection fraction, or use of secondary prevention medication. This is observed across multiple geographic regions and ethnicities, despite marked disparities in the prevalence of diabetes. ClinicalTrials identifier ISRCTN43070564

Purpose and backgroundThe specialized literature has a low degree of information regarding the origin of the inferior thyroid artery (ITA). Our study was performed on computed tomography angiographies (CTAs), and the following aspects were observed: the origin of the ITA from the subclavian artery (SCA) or thyrocervical trunk (TCT), taking note of the distance of the origin of the ITA in relation to the origin of the SCA or the corresponding TCT, as well as the origin of the ITA, comparing right to left and according to gender. MethodsOur study was realized on a total of 108 ITA (64 on the right side and 44 on the left, with 48 in male subjects and 60 in females), analyzed on CTA. ResultsFrom the 108 arteries, we found the origin of ITA directly from the SCA in 31.48% of cases, and in 68.52% from the TCT. The distance between the origin of the right SCA and the origin of the corresponding ITA, was between 29.1-53.1 mm, while on the left side, the same distance was between 43.7-68.1 mm. The distance between the right TCT and the origin of the right SCA, was between 22.5-75.0 mm, and for the left side, it's between 48.7-56.8 mm. ConclusionsThe inferior thyroid artery is one of the arteries most susceptible to variations in terms of origin and size.With differences between the two sides (right and left), as well as differences related to gender.

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The authors present a retrospective study over a period of 18 years on electrocutions that were included electrocutions through direct contact (as the clinical presentation) or that were produced by high voltage or low voltage, which aims at extracting conclusions prognostic and therapeutic nature and especially the final therapeutic results, the study concluded that even electrocutions is decreases incidence, mortality of electrocutions with high voltage remains strong.

Carpal tunnel syndrome is a sensitive neuropathy of the upper limb caused by chronic compression of the median nerve. The presented study focused on highlighting the value of morphological changes of the median nerve - shown by MRI in the management of carpal tunnel syndrome. The study group included 23 patients, adults, treated in the Plastic Surgery Clinic of the County Emergency Clinical Hospital in Constanta - prospective study. Magnetic resonance imaging allowed accurate measurement of the median nerve diameter and showed significant decreases in most cases, which suggested an advanced stage of the disease - morphological changes being corroborated with clinical ones. This imagistic investigation opens a new way in establishing the surgical indication, which is required in case of reduction of the nerve diameter by at least 1.5mm at the site of compression. The criterion of diameter decrease can be a benchmark in order to establish a therapeutic algorithm in carpal tunnel syndrome.