This study aimed to investigate the effects of heavy metals on measures of male fertility. One hundred and two infertile men with occupational exposure and thirty fertile men were included in this study. Blood and urinary levels of lead, cadmium, zinc and copper were measured by atomic absorption spectrophotometry. Semen parameters and a motile sperm organelle morphology examination were also performed. Measures of hormonal levels, oxidation–reduction potential, DNA fragmentation index and chromatin condensation were assessed for all participants. Heavy metals levels, oxidative stress and DNA quality were significantly higher in the infertile group compared to controls. FSH and testosterone levels were lower in the infertile group. A urinary cadmium level was positively associated with abnormal sperm morphology (r = .225, p < .05). Normal morphology was inversely correlated with the duration of the exposure (r = −.227, p = .022). The blood lead level was positively related to the level of testosterone (r = .223, p = .031). Cadmium and lead blood levels were positively correlated with the level of chromatin decondensation (r = .528, p < .001; r = .280, p = .017). Our study showed that occupational exposure to heavy metals is very harmful to reproductive health. DNA quality and oxidative stress investigations must be recommended for reprotoxic exposed patients prior to in vitro fertilisation treatment.

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INTRODUCTION L'ethmoïdite aiguë (EA) est l'infection bactérienne des cellules du labyrinthe ethmoïdal. Il s'agit d'une infection sévère, nécessitant un diagnostic et un traitement urgents du fait du risque de complications ophtalmologiques et endocrâniennes [1].Elle survient le plus souvent entre l'âge de 6mois et 5 ans. Le signe d'appel est l'apparition dans un contexte fébrile d'un oedème palpébral [2]. Le traitement repose essentiellement sur l'antibiothérapie à large spectre. La chirurgie est réservée aux formes compliquées. Le but de notre étude est d'analyser les caractéristiques clinico-radiologiques et thérapeutiques de cette affection à travers 11 observations et une revue de la littérature.