Rehabilitation of mutilated dentition is esthetic and functional challenge. The present condition of dentition, patient’s level of motivation for maintaining oral hygiene, social status etc are the key factors to successful rehabilitation. Maxillary teeth supported overdenture against mandibular complete denture is a potential risk for enhancing residual ridge resorption of mandibular arch. In such situation mandibular implant prosthesis is a better treatment option. In this case report a comprehensive management of patient with mutilated dentition has been carried out in phased manner.Here three roots with healthy periodontium were preserved in maxillary arch. Fixed implant prosthesis was made in mandibular arch. Presently patient has been followed up for 6 years and found to be highly satisfied and having a good oral hygiene. Maxillary overdenture against mandibular fixed implant prosthesis should be considered as effective rehabilitative modality in rehabilitating such cases.