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Nowadays, there is a tendency for an increasing prevalence of metabolic syndrome (MS) among middle-aged patients. It seems relevant to determine the quality of life in patients with MS and cognitive impairment (CI) in this age group. Aim of the study. Studying the quality of life in patients with MS and CI. Material and methods. In total, 208 people were examined. Out of a total number, 178 patients were divided into 2 groups: some were diagnosed with MS and CI, and some patients had MS but no cognitive deficit. The comparison group consisted of 30 healthy individuals of comparable age. All patients underwent neuropsychological testing. The method of cognitive evoked potential (P300) with the use of EMG/VP Nicolet Viking Select was chosen to quantitatively assess cognitive functions of the patients. Quality of life was assessed by the use of SF 36. Results and discussion. In the group with MS and CI, compared with patients who have MS but no cognitive disorders, the indicators of general health were lower (52.30±13.90 and 58.22±10.96 points, respectively, p<0.05), physical functioning (69.23±19.79 and 77.13±15.46 points, respectively, p<0.05), emotional role functioning (42.17±21.79 and 56.93±19.84 points, respectively, p<0.05), self-assessment of mental state (53.68±11.84 and 58.39±12.4 points, respectively, p<0.05). In patients with MS and cognitive disorders, a strong association was found between the results of the MMSE test (r=0.39; p=0.015), the Wechsler memory test score (r=0.29; p=0.014), the FAB test score (r=0.43; p=0.018), and physical functioning scores. Mental health scores were associated with the results of the Wexler test (r=0.27; p=0.014). In the group with MS and CI, there was a positive correlation between the amplitude of P300 and indicators of physical functioning (r=0.40; p=0.016). Findings. In the group of patients with MS and CI, compared with patients without cognitive disorders, there is a decrease in the quality of life, especially in indicators of physical functioning. The quality-of-life parameters of patients with MS are associated with cognitive functions determined both by neuropsychological testing and by P300.

The results of a study aimed at assessing the potential use of millimeter therapy in the treatment of anxiety in elderly patients are presented. The aim of the study was to assess the potential use of millimeter therapy in the treatment of anxiety in elderly patients. Materials and methods. A comparative study of the effectiveness of EHF-therapy in the treatment of elderly patients with anxiety, against the background of chronic forms of coronary heart disease in the form of angina of tension of the first-third functional classes and arterial hypertension of the first or second degree of the fourth class of risk of cardiovascular complications. The total number of patients was 92 people. (men – 44, women – 48). Patients were divided into 2 groups. Patients of the clinical observation group (n = 45) during treatment of the main somatic disease additionally received EHF-therapy sessions, patients of the control group (n = 47) received only drug therapy for the somatic disease and phytotherapeutic drugs to alleviate anxiety symptoms. To assess the dynamics of anxiety and quality of life, a brief questionnaire SF-36 was used. Results and discussion. Before treatment, patients in the main group had reduced quality of life indicators on the scales: general health (GH) by 31.3 ± 2.0 points, role-based functioning (RP) - by 24.2 ± 3.1 points, pain (P) - by 20.6 ± 4.2 points, physical functioning (PF) - by 23.8 ± 2.0 points, vitality (VT) - by 26.1 ± 4.2 points, psychological health (MH) - by 37 , 8 ± 3.8 points, role-based emotional functioning (RE) - by 30.6 ± 3.5 points and social functioning (SF) - by 32.2 ± 2.1 points. At the end of treatment, there was a positive trend in the quality of life. It was noted that with concomitant alarming symptoms of cardiovascular pathology, the severity of cardiac pain syndrome was significantly (p < 0.05) compared with the value of the indicator before treatment, and indicators of physical and social functioning increased. Findings. It is shown that the inclusion of millimeter therapy in the treatment of anxiety in elderly patients with cardiovascular pathology contributes to a significant improvement in symptoms and quality of life. The inclusion of millimeter therapy in treatment programs improves their effectiveness, which consists in reducing the severity of anxiety symptoms in older people, and increases resistance to stress factors by forming an adequate behavioral stereotype.