On the territory of the Ivano-Frankivsk region were found 66 species of regionally rare bryophytes. Among them, mosses predominat, but the proportion of liverworts is significant. Based on the analysis of the taxonomic structure, it was established that the liverworts (Marchantiophyta) belong to 2 classes, 4 orders, 13 families, 16 genera, 19 species; mosses (Bryophyta) – to 3 classes, 12 orders, 20 families, 38 genera, 47 species. According to the number of species, bryophyte families are located as follows: Pottiaceae – 11 species (16,8 %); Brachytheciaceae – 5 (7,6 %); Cephaloziaceae and Splachnaceae – 3 (4,6 %), the rest of the families are oligo- and monospecies. Among rare species, the boreal geographical element predominates (27 species, 41,0 %), the following arid (11 species, 16,7 %), and nemoral (10 species, 15,1 %). The analysis of ecological groups of mosses and liverworts by type, chemistry, humidity, trophic and illuminance of the substrate is carried out. It was found that most rare species belong to the epigeous heliophytes. The chemistry of the substrate is dominated by acidoneutrophils, which grow on substrates with pH values from 3 to 7. The trophic dominance of species that occur on relatively nutrient-rich substrates; the humidity of the habitats is dominated by mesophytes, a significant hygrophytic group of species. Among the rare bryophytes, species with life forms of low turf, which occur mainly on soil and rocks, predominate. Most rare species with life forms of mats, tall turfs and wefts are confined to wetlands (swamps and shores of reservoirs), a significant part mat and short turfs – to rock outcrops. Sexual types of bryophytes and the presence of specialized organs of asexual reproduction have been determined. Rare species, confined to wet and humid ecotopes, are particularly sensitive to any changes in hydrothermal conditions.