Graves' disease (GD), an autoimmune disorder resulting from thyrotropin (TSH) receptor stimulation by autoantibodies, is an uncommon disease in children. The incidence of GD is thought to be rising and is currently about 0.1 per 100,000 person-years in young children to 3 per 100,000 person-years in adolescents. The estimated prevalence varies between countries, from 1/10,000 in the United States to 1/100,000 person-years (for children aged 0-15 years) in the UK and Ireland. We reported one female patient, 14 years old, complained neck lump accompanied by exophthalmos, palpitation especially at night, followed by easily sweating all over her body. That manifestation also followed by increased of appetite, sleep disturbance, agitated, and behavioural changes those affecting her school report. Physical examination revealed hypertension, tachycardia, proptosis of both eyes, a non-pain palpable soft diffuse symmetrical mass on front neck followed down when swallowing, a systolic murmur, sweating on palms and soles of the feet. Laboratorium investigation was found FT4 >100,000 ng/dL (0.93-1.70); TSH s <0.05 IU/mL (0.27-4.20); T3 Total 28.6 nmol/L; TRAb 36.5 IU/L (≤1.75) and an ECG result found sinus tachycardia. Patient was treated with thyrozol (thiamazole) and propranolol. We need to increase awareness to adverse event of antihyperthyroid drugs, remission rate, predictor factors in successful treatment to get a better long-term outcomes of medical therapy in Grave's disease.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.