Social media (SM) has become indispensable for individuals and workplaces/organizations in Africa and beyond. Therein, ethical concerns are posed due to the inability to create virtual boundaries (VM), the intractability of guidelines for managers and other unintended risks/con­sequences. Operations research was used for modeling ethical concerns but have been defeated due to reasons of several ethical values and various assessment criteria for stakeholders. Conse­quently, this review paper initially x-rays the import of ethical dilemmas in older studies so as to conceive a strategy characterized by engaging stakeholders that utilize SM via Agent-Based Modeling (ABM), in such a manner that ethics can be evaluated. Additionally, it presented the rudiments of social media ABM explorations and the peculiarities of Africa. Finally, the review provided a suitable methodology and sheds light on the possible challenges of ABM implementation. Besides the benefit of increased patronage, the agent technology may also constitute a pedagogical tool for learning ethical behavior. Moreover, it is our hope that with the involvement of experts of related disciplines in Africa, attendant theories are formalized and used for building agent models that allows ethical decision making, weighing of pros and cons, analyzing differences and dimensions inherent in VM creation.