Curcumin is a chemical found in the Curcuma xanthorrhiza rhizome that has a variety of pharmacological properties. However, it is unknown whether the extraction conditions have a significant effect on the extracted curcumin from C. xanthorrhiza. In this research, the effects of extraction conditions (i.e., particle size, extraction solvents, and extraction methods) on curcumin content from C. xanthorrhiza rhizome were studied by doing a meta-analysis. An article search was performed in ScienceDirect, Garuda Portal, Google Scholar, and the IPB Repository database. Research data produced during the identification and selection phases were then classified, processed, and entered into the metaanalysis statistical program and then analyzed. The maximum curcumin was obtained using extraction conditions with n-hexane as a solvent, 100 mesh for particle size, and Soxhlet for the extraction method. Particle size and extraction method correlate and influence curcumin content; however, solvent extraction does not. This review will highlight how the effectiveness of the extraction of curcumin compounds from C. xanthorrhiza rhizome so that it can be used for extraction at the industrial level.