A patient with haemolytic disease of the newborn (HDN) due to anti-M which
required exchange transfusion is described. Anti-M antibodies are usually assumed
to be naturally occurring and to consist of immunoglobin M (IgM); many
however have an immunoglobin G (IgG) component. In view of this and the described
occurrence of HDN, recommendations are made regarding the management
of a pregnancy in which anti-M antibodies are detected.
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