'Сумський державний педагогічний університет ім. А.С.Макаренка ін с т и т у т гігієни та медичної екології' ім. О.М.Марзеєва А М Н України, м. Київ 'A.5. Makarenko Sumy state pedagogical university 2A.N. M arseyev Institute of hygiene and medical ecology of A M S of Ukraine, Kyiv At the modem stage o f development o f hygienic science the efficiency o f prevention o f occupational stresses is determined by the quantitative estimation o f factors in the development o f pre-pathological states. With the purpose to develop a quantita tive criterion for estimation o f the probability o f development o f occupational burnout syndrome in teachers of general edu cational establishments 77 teachers have been examined aged from 31 to 60 with work experience from 5 to 33 years and of three pedagogical categories. As a result o f the conducted research it was established that high level o f occupational burnout syndrome is accompanied by changes in spectral indices o f cardiac rhythm variability, mainly o f the sympathetic circuit, in regulation o f the cardio-vascular system, pointing out to the strain o f regulatory systems in teachers with high level o f neuroemotional strain. Basing on the obtained findings an individual integral index o f probability in development o f occupational burnout syndrome in teachers has been developed.