A 4-year-old girl presented with a nasopharyngeal rhabdomyosarcoma and had the characteristic features of the naevoid basal cell carcinoma syndrome. She was treated with a modified standard combination of chemotherapy and radiotherapy. However, radiotherapy had to be interrupted because of severe radiation recall.

Two children with disseminated malignant sacrococcygeal tumour were treated with six courses of vinblastine, cis-platinum, and bleomycin. Both had exploratory operations after four courses of treatment and no histological evidence of malignant disease was found. The two children have remained free of disease with normal alpha-fetoprotein levels for 30 months and 18 months, respectively.