Flipped classroom method with the infusion of interactive digital media into teaching and learning has altered instructional strategies in educational institutions. In this study, the flipped classroom method was conducted online using the ECOPRENEUR learning portal which can be reached at http://digitent.my/. The online learning platform was used to teach Principles of Entrepreneurship (ENT 600) over one semester. This study describes the use of a completely virtual flipped classroom which differs than a blended mode that involves online and face-toface meetings. Eighty-eight students took part in this study. Three instruments comprising survey, structured interview, and students' final grade for the subject were used to gauge students' perception and outcome of using the flipped classroom method in the ECOPRENEUR learning portal. The results show a positive response to the flipped learning using the ECOPRENEUR learning portal.