The objective of the research was to study the dynamics of health indices of children and adolescents of the city of Saint Petersburg for 20 years. We analyzed official statistical data of general and primary morbidity rate of children aged of 0-14 years and adolescents aged 15-17 years, the incidence of chronic diseases in schoolchildren (7-17 years), as well as there was held a comparative analysis of the health state of senior schoolchildren in 5 Saint Petersburg schools with advanced content of education based on indices of the pathological prevalence rate, physical development, non-specific resistance, adaptation status. The study was executed according to approved standard methods. In the study, over a 20-year period there was revealed a steady trend of health deterioration of children and adolescent population of the city as a whole, and schoolchildren enrolled in the program with advanced content of education as well. The prevalence rate of diseases in children has increased by 72.0%, while primary morbidity increased by 70.4%. Adolescents aged 15-17 years showed more pronounced gain of indices than in children, the level of general and primary morbidity rate has increased by 2 times. In the structure of general and primary morbidity of children and adolescents first ranking places were held by respiratory diseases, injuries, poisoning, diseases of the skin and subcutaneous tissue. In chronic morbidity of schoolchildren there were prevailed diseases of the musculoskeletal system, diseases of the eye and its appendages, respiratory diseases. There was established the gain in the pathological prevalence rate in schoolchildren with advanced content of education. In the majority of the surveyed high school students there were diagnosed polysystemic changes in health status. Negative trends in the health status of children and adolescents of the city of Saint - Petersburg were confirmed by indices of nonspecific resistance: immunological tests, key elements of protective enzyme systems of the body. In order to stabilize the growth of children and adolescent incidence there were suggested directions of prevention work.

Introduction the aim of the study. The implementation of risk-oriented model organization of the control and supervision activities of Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing with the assessment system of potential dangerous objects requires the creation of multiannual reliable database about the occupational working conditions which must include results of the production control for enterprises of all industries of the national economics of the Russian Federation. The aim of the study was to study the effectiveness of the use of the production control (PC) results of working conditions for the provision of sanitary - epidemiological wellbeing of the population. Material and methods. The study was conducted on materials of Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing on the Leningrad region, Petrostat for 2009-2012. In analysis there were included software and PC results of working conditions in 420 industrial enterprises of various branches of the Leningrad region industry. To develop a regional model of PC program planning based on critical control points there was chosen the major refinery in the Leningrad region - Limited Liability Company “Production Association” Kirishinefteorgsintez “(LLC “PA “KINEF”). 3960 protocols of laboratory and instrumental investigation results of working conditions were made for the purpose of PC control on LLC “PA “Kinef” and 1921 protocols of PC results - on 420 industrial enterprises of the Leningrad region were analyzed. Results. The performed analysis revealed a number of problems to the application of PC results for the aim of working conditions optimization of employees, planning disease prevention program and the assessment of object’s sanitary-hygienic wellbeing. The method of critical control points (CCPs) in the planning of PC programs on the large industrial enterprises is proposed to use. On the example of “Kinef” there was shown the efficiency of the use of CCPs in order to optimize the PC programs. There was developed and implemented the regional model of the use of PC programs which allows to solve the problem of the significant increase of preventive orientation and efficiency of PC program at enterprises of all sectors of the national economy of the Russian Federation as an important element of the management of sanitary - epidemiological population wellbeing regarding to the maintenance of healthy and safe working conditions. Conclusions. Existing legal regulatory and methodological framework regulating the organization and performance of PC control and social - hygienic monitoring in the Russian Federation requires significant changes and additions what allow to increase the reliability of the objects classification on groups of sanitary-epidemiological wellbeing and to realize a risk-oriented approach to control and oversight activities.

Contemporary research reveals that electronic devices for nicotine consumption produce not so negative effects on health due to adverse chemicals being emitted in substantially lower quantities. Nevertheless, such consumption still results in emission of various organic and non-organic substances with their effects on health being rather unpredictable. It is necessary to conduct additional studies, including those focusing on passive smoking of electronic cigarettes and assessing health risks caused by exposure to them. Our research goal was to assess acute health risks caused by passive consumption of tobacco and nicotine-containing products. We built a model for tobacco or nicotine consumption by actual consumers (volunteers) and the process was evened as per a number of consumption sessions. We examined three products: tobacco cigarettes (cigarettes), electronic nicotine delivery system (ENDS), and a tobacco heating system (IQOS). Background air quality parameters were measured in a specifically organized enclosed space prior to each study session. We also conducted experiments in so called «reference groups» when research participants didn’t consume the examined products but were in the same conditions. Health risks were assessed as per the Guide R 2.1.10.1920-04 «The Guide on assessing health risks caused by exposure to chemicals that pollute the environment». Use of ENDS and IQOS does not result in significant changes in air composure and does not cause unacceptable acute health risk. Combined effects produced by contaminants on organs and systems resulted in health risks for respiratory organs, eyes, and body as a whole being insignificantly higher than permissible levels; these risks were practically the same as those detected for a reference group. Tobacco smoking resulted in unacceptable acute risks 1.5 hours after an experiment started; these risks were caused by elevated concentrations of such contaminants as acetaldehyde, formaldehyde, PM2.5, PM10, and carbon monoxide.

Introduction. Macromycetes include mercury compounds in their metabolism processes. The method for assessing the contamination of the soil layer (topsoil) by mercury by estimating the mercury content in the mushrooms is accessible and sufficiently informative. Mercury is a persistent inorganic ecotoxicant, it enters the human body from the environment. This process requires constant monitoring of the content of this hazardous metal in the environment and the in biomaterials of the human organism. Material and methods. The object of the study was selected bracket macromycetes growing on open soil areas: lawns, boulevards, parks, squares, etc. There were studied representatives from the fungal families as follows: Agaricacea, Boletaceae, Russu-laceae, Coprinaceae. Mushrooms were collected in the stage of sporulation, in the spring-summer-autumn period from 2002 to 2017. The determination of mercury in fungi was performed by atomic absorption method on specialized mercury analyzers of the “Julia” series (detection limit of 1 ng/g, the error of the method is not more than 15%). Mercury content in hair was determined in 1153 St. Petersburg residents aged from 0 to 80 years using atomic emission and mass spectrometry methods with inductively coupled argon plasma on devices Elan 9000 (Perkin Elmer, USA) and Optima 2000 V (Perkin Elmer, USA). Results. The results of the analysis of mushrooms collected in 2017 on one of the green streets of the industrial district of Saint-Petersburg demonstrate a high degree of mercury contamination of the megapolis. Mushrooms (Cinereus comatus) were collected at three locations of Alameda, separated by approximately 100 m, and were analyzed for the content of mercury in them. The following values of mercury in mushrooms were got is a 0.61 mg/kg, 0.83 mg/kg and 0.35 mg/kg. The hair of 1153 inhabitants of St.-Petersburg has been analyzed for mercury content. The highest concentrations of mercury have been established to be set at working population aged 18-64 years. This fact can be explained by the professional activities associated with the contact with mercury and active way of life, particularly with greater frequency of the use in the diet of mushrooms and other products, being potential sources of mercury. Discussion. The performed studies show the mercury concentration to be not only generalized but also stable. The pollution of the territory of St. Petersburg is little different from the pollution of the territories of other cities, where the mercury content in mushrooms is also found to be high in comparison with the permissible level. Conclusion. The obtained data indicate a high stable contamination of the territory of St. Petersburg and its nearest suburbs with mercury. Mercury and its compounds in environmental objects (mushrooms) can present the real danger to the health of the population, therefore there is a need for non-invasive monitoring of the content of mercury in biomaterials of the human organism and environmental objects.

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