(32% response rate) showed that the feedback report had an appropriate format and length (median scores 3/5), although only 33% of the stewards had disseminated the results to colleagues. Conclusion and relevance Awareness of electrolyte disorders increased among physicians, but the direct impact of our feedback remains unclear. Other QIs showed little room for improvement and need re-evaluation. Overall results suggested a persistent need for training on intravenous fluids, especially on surgery wards, and feedback should include tailored communication with staff.
Background and importance Cancer patients are a vulnerable population for SAR-CoV-2 infection. Aim and objectives The aim of our study was to describe the epidemiology and clinical course of patients with cancer infected with SARS-Cov-2, attending hospital. Material and methods A retrospective observational study was conducted in cancer patients attending a tertiary hospital for SARS-CoV-2 infection during the period 3 January 2020 to 31 May 2020. Demographic and clinical variables were analysed: comorbidities, tumour diagnosis, tumour stage and whether they had received anticancer treatment in the last month (active treatment). The clinical course was evaluated by hospital admission, pneumonia, oxygen therapy requirements, the development of acute respiratory distress syndrome (ARDS), admission to ICU, mortality rate and mortality rate <30 days from admission. Quantitative variables were expressed as means (SD). The association between dichotomous variables or proportions was compared using Fisher's exact test and between quantitative variables using the Mann-Whitney U test. Results 112 patients were included, 59.8% (67) were men, mean age 67±13.4 years. 94.6% (106) were Caucasian (4.4% (5) Latino). 61.6% (69) were non-smokers, 25% (28) exsmokers and 13.4% (15) current smokers; 11.6% (13) had obesity. The most frequent comorbidities were: 57.1% (64) arterial hypertension, 34.8% (38) cardiovascular disease, 32.1% (36) diabetes mellitus and 21.4% (24) COPD. The most frequent cancer diagnosis were: 18.8% (21) breast cancer, 17.9% (20) lung cancer, 16.1% (18) colorectal cancer and 12.5% (14) prostate cancer. Tumour stage: 55.4% (62) metastatic disease, 25% (28) localised disease and 19.6% (22) locally advanced disease. 60.7% (68) of patients received active cancer treatment (42.7% chemotherapy, 32.3% hormonal treatment, 16.2% targeted therapy, 7% immunotherapy and 2.9% radiotherapy). At admission, 85.7% (96) of patients
BackgroundThe Treatment Satisfaction Questionnaire for Medication (TSQM) was designed to assess patient treatment satisfaction in chronic diseases. Its performance can be used in multiple sclerosis (MS).PurposeTo compare treatment satisfaction in four domains: effectiveness, side effects, convenience and global satisfaction in patients with MS who attended an outpatient pharmacy department.Material and methodsThe study was conducted in a tertiary hospital in Madrid, Spain. Eligible patients were those who had received one of the following treatments for at least 4 months: subcutaneous interferon β-1a (SC IFNβ-1a) 125 μg, Plegridy; SC IFNβ-1a 22/44 μg, Rebif; SC IFNβ-1b 250 μg, Betaferon; glatiramer acetate (GA) 40 mg, Copaxone; oral (PO) teriflonomide, Aubagio; PO dimethyl fumarate (DMF), Tecfidera; or PO fingolimod, Gilenya. Patients were asked to complete the TSQM questionnaire. Furthermore, the pharmacist registered any adverse drug reactions the patients could have suffered during the last month.Results60 patients (41 women) with a median age of 44±11 years were included in the study. The most used treatments were SC IFNβ-1a (15 patients) and DMF (12). Treatment satisfaction scores were 71.4 (71.4–85.7) for effectiveness, 90.0 (75.0–96.3) for side effects, 78.6 (71.4–90.4) for convenience and 76.5 (70.6–88.2) for global satisfaction (out of a maximum of 100). There were statistically significant differences among the different patients´ treatment satisfaction scores in terms of side effects (p=0.0034) and convenience (p=0.0041). However, no differences were found for effectiveness (p=0.8339) or global satisfaction (p=0.8711). When comparing PO versus SC treatments, there were important differences in terms of sides effects (p=0.0027), but global satisfaction remained non-significant (p=0.6204). Most reported side effects were injection site reactions (71.1% of patients with SC treatment) and flu-like symptoms for IFN administrations (54.9%). Patients reported gastrointestinal adverse symptoms for DMF (83.3%). Fingolimod was the best tolerated treatment (all 5 patients reported no adverse effects).ConclusionPatients with MS who attended our outpatient pharmacy department were satisfied in terms of effectiveness, side effects, convenience and global satisfaction. Differences in the profile of side effects were remarkable but these did not t affect effectiveness or global satisfaction.No conflict of interest
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