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The aim of the study was to analyze the scientific medical literature on the cardiac manifestations of SARS-CoV-2 virus infection.

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Aim. To evaluate the effectiveness and safety of the use of artificial chords using polytetrafluoroethylene sutures during mitral valve replacement in patients with rheumatism. Methods. The study included 134 patients operated on for isolated rheumatic mitral valve disease. Immediate (10 days) and long-term (24 months) results were evaluated in the three groups of patients, depending on the method of valve replacement: creation of prosthetic chords using polytetrafluoroethylene sutures (37 patients), preservation of native chords (67 patients), total excision of the subvalvular apparatus (control group, 30 patients). Results. 24 months after surgery in the group of prosthetic chords and the group of preserved native chords recorded was a significant decrease in the pulmonary artery pressure, the left atrial size and a reduction in the end-diastolic left ventricular size. In the control group of patients reported was a reduction in left ventricular ejection fraction in long-term follow up. Conclusion. The use of polytetrafluoroethylene sutures in order to create new chords demonstrated their safety and effectiveness in preserving the physiological left ventricular geometry; artificial chords, as well as the preserved native chords, have a positive effect on the left ventricular contractile function in the remote postoperative period.

Aim. To evaluate to effectiveness and safety of the functional technique of measuring the length neo-chords during reconstructive operations on the mitral valve for degenerative mitral regurgitation. Methods. The study included 34 patients, in whom the method of chord prosthesis with polytetrafluoroethylene sutures was used for correction of the anterior and/or posterior mitral valve leaflet prolapse. In order to determine the length of the chords a technique of functional hydraulic tests with a sliding suture knot was used by pressure infusion of a cold isotonic sodium chloride solution into the left ventricle until optimal geometry and competence of the valve leaflets was achieved. Results. No perioperative deaths were registered. The average postoperative length of hospital stay was 10±3.1 days. In 97% of the cases this technique made it possible to obtain immediate satisfactory hemodynamic results of the reconstruction. In long-term follow-up (13 months) 1 (3%) patient was re-operated for severe mitral regurgitation that was associated with the detachment of a native anterior leaflet chord, which was discovered during the operation. The two neo-chords epithelialized, became macroscopically indistinguishable from the native chords, and could be identified by the knots on the atrial side of the leaflet, their integrity was not compromised. In all other cases long-term follow-up after the operation showed a satisfactory hemodynamic functionality of the mitral valve. 76% of the operated patients had postoperative echocardiographic examination performed in our center. In 42% of patients there was no insufficiency, 44% of the patients had 1st degree regurgitation, in 14% of patients the regurgitation was classified as 1-2 degree with no signs of left atrium volume overload, left ventricular dysfunction or symptoms of heart failure. Conclusion. The functional technique for determining the length of neo-chords is an effective and safe method that makes it possible to successfully perform reconstructive operations for degenerative mitral regurgitation.