The article is devoted to the problems of labour productivity increase. It studies trends in labour productivity growth in 12 developed countries and presents a comparative analysis of individual factors that directly affect labour productivity indicators in some European countries as well as the USA and Japan. The article examines and analyzes the reasons for Russia’s lagging behind the developed countries of Europe and the USA in terms of labour productivity; the detailed analysis of the level and dynamics of labour productivity in the Russian economy is given. The authors of the article calculated indicators of labour productivity, indicators of the ratio of the average wage growth rates in the economy of the Samara region. Special attention is paid to the study of organizational and socioeconomic factors of increasing labour productivity in conditions of limited financial resources.

The article views rationalization of working time as the most important factor of the labor productivity of personnel. Rationalization of working time is aimed at reducing losses and unproductive costs caused by deficiencies in the system of production support, its management and organization. Improving the use of working time, it is possible to increase productivity of labor very quickly without attracting additional funding. This stipulates the relevance of the study of the issues of efficient use of working time and reducing its losses and unproductive costs. The objectives of the study, the results of which are reflected in this article, were the analysis of the problems connected with inefficient use of working time at Russian enterprises and the search for ways to solve them as well as the development of an algorithm for calculating and evaluating working time efficiency. The authors of the article justified the procedure for evaluating the efficiency of working time, analyzed the structure of work at the preparatory and final stage and the time of workplace maintenance, the composition of losses and unproductive use of working time. Calculating of the possible increase of labor productivity due to better use of working time on the example of one of Samara enterprises is given. A flowchart of the analysis of working time efficiency and the assessment of reserves for labor productivity increase are presented; the main directions of improving the use of working time at enterprises are given, taking into account the reasons of its losses and unproductive costs.

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Background: The aim of this study was to assess the real-world effectiveness and safety of certolizumab pegol (CZP) in rheumatoid arthritis (RA) patients, and the impact on patients’ productivity, pain, and fatigue, in Canadian practice. Methods: FαsT-CAN, a 2-year prospective, observational study, evaluated CZP use in Canadian adults with moderate to severe, active RA. The primary objective was to assess the proportion of patients achieving 28-joint Disease Activity Scores (DAS28) <2.6 at Week 104. Secondary and additional endpoints assessed the improvements in Patients’ Assessment of Arthritis Pain (PtAAP), fatigue, Health Assessment Questionnaire-Disability Index (HAQ-DI), and the proportion of patients achieving minimal clinically important differences (MCID) in HAQ-DI. Validated arthritis-specific Work Productivity Surveys (WPS-RA) assessed the RA-associated impact on productivity. Incidence of CZP-related treatment-emergent adverse events (TEAEs) was reported for patients receiving ⩾1 dose of CZP (safety set). Results: The full analysis set (baseline DAS28 ⩾ 2.6, ⩾1 dose of CZP and ⩾1 valid post-baseline DAS28 measurement) included 451 of the 546 patients recruited into the study; a total of 229/451 (50.8%) patients completed Week 104. At Week 104, 90/451 (20.0%) patients achieved DAS28 < 2.6. Rapid improvements in disease activity, pain, and fatigue were observed. At Week 104, 66.2% of patients achieved HAQ-DI MCID. Patients employed at Week 104, reported reduced absenteeism, and improved productivity. CZP-related TEAEs were consistent with the known CZP safety profile. Conclusions: CZP was an effective RA treatment in Canadian practice, and no new CZP-related safety signals were identified. The improvements in household and workplace productivity are the first observations in a real-world Canadian setting.

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