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In this work, use of pulmonary bronchophonography for functional evaluation of respiratory system was analyzed in early-aged patients with bronchial asthma. A computerized acoustic diagnostic complex Pattern-01 was used for this purpose. The breathing pattern was analyzed using amplitude and frequency characteristics of respiratory sound spectrum. The study involved 520 children with asthma aged 1 to 4 yrs (mean age, 2.8 ± 1.1 yrs, 294 males and 226 females) followed-up in the pediatric clinic of Moscow Medical Academy. Fifty healthy children were as controls. We investigated frequency and amplitude spectrum of respiratory sounds in exacerbated and stable asthma. High-frequency acoustic component of work of breathe was significantly different in healthy and in patients with asthma exacerbation. We have selected breathing patterns that could be further applied. Pulmonary bronchophonography allows monitoring lung function and assessing efficacy of treatment in asthma. It is an effective, noninvasive and simple method which is of special importance for detecting functional disorders in early-aged children.

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