Gastric lavage in patients with acute poisoning is an important component of the complex of detoxification activities at the pre-hospital stage of medical care. Non-compliance with the rules of gastric lavage may result in iatrogenic complications, among which 4.9% are gastric injuries by the probe. The analysis of treatment of 8,926 patients poisoned with non-cauterizing substances was performed. In 44 of them (0.5%), there were signs of gastroduodenal bleeding, caused by trauma of the gastric mucosa and in 12 patients (0.13%), there was perforation of a gastric wall by a probe. The main method of endoscopic hemostasis in patients with bleeding was infiltration hemostasis with epinephrine solution, with the exception of 5 patients with bleeding of type F1a and F2a, where the combined hemostasis with argon-plasma coagulation was performed. All 12 patients with gastric perforation were urgently operated. Prevention of gastric trauma during lavage at the prehospital stage is the strict implementation of the procedure developed by the staff of the Center for Treatment of Acute Poisoning at the